MicroRNA expression profiling of CCl4-induced liver fibrosis in Mus musculus

ABSTRACT: To investigate the differences in microRNA expression profiles between fibrotic and normal livers, we performed microRNA microarrays for total RNA extracts isolated from mouse livers treated with carbontetrachloride (CCl4) or corn-oil for 10 weeks (n=3/group). MicroRNAs were considered to have significant differences in expression level when the expression difference showed more than two-fold change between the experimental and control groups at p<0.05. We found that 12 miRNAs were differentially expressed in CCl4-induced fibrotic liver.

ORGANISM(S): Mus musculus

PROVIDER: GSE77271 | GEO | 2016/03/22

SECONDARY ACCESSION(S): PRJNA309936

REPOSITORIES: GEO