Ontology highlight
ABSTRACT:
INSTRUMENT(S): [MOE430A] Affymetrix Mouse Expression 430A Array
SUBMITTER: Myoung Ho Jang
PROVIDER: GSE77545 | GEO | 2016-02-04
SECONDARY ACCESSION(S): PRJNA310763
REPOSITORIES: GEO
Sugawara Reiko R Lee Eun-Jung EJ Jang Min Seong MS Jeun Eun-Ji EJ Hong Chun-Pyo CP Kim Jung-Hwan JH Park Areum A Yun Chang Ho CH Hong Sung-Wook SW Kim You-Me YM Seoh Ju-Young JY Jung YunJae Y Surh Charles D CD Miyasaka Masayuki M Yang Bo-Gie BG Jang Myoung Ho MH
The Journal of experimental medicine 20160307 4
Eosinophils play proinflammatory roles in helminth infections and allergic diseases. Under steady-state conditions, eosinophils are abundantly found in the small intestinal lamina propria, but their physiological function is largely unexplored. In this study, we found that small intestinal eosinophils down-regulate Th17 cells. Th17 cells in the small intestine were markedly increased in the ΔdblGATA-1 mice lacking eosinophils, and an inverse correlation was observed between the number of eosinop ...[more]