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Primary human blood-derived macrophages (BDMs): control vs. infected

ABSTRACT: Transcriptional profiling of primary human blood-derived macrophages (BDMs) comparing control untreated BDMs with BDMs exposed with Streptococcus pneumoniae strain D39 (MOI 0.1 and 0.5) for 16 hours)

ORGANISM(S): Homo sapiens

PROVIDER: GSE77561 | GEO | 2016/06/15

SECONDARY ACCESSION(S): PRJNA310851

REPOSITORIES: GEO

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Primary human blood-derived macrophages (BDMs): control vs. infected

Project description:Transcriptional profiling of primary human blood-derived macrophages (BDMs) comparing control untreated BDMs with BDMs exposed with Streptococcus pneumoniae strain D39 (MOI 0.1 and 0.5) for 16 hours) Two-condition experiment, control BDMs vs. infected BDMs. Biological replicates: 3 control replicates, 3 infected replicates MOI 0.1, 2 infected replicates MOI 0.5).

2016-06-15 | E-GEOD-77561 | biostudies-arrayexpress

Affymetrix microarray of human monocyte derived macrophages following challenge with Streptococcus pneumoniae with or without pneumolysin

Project description:Transcriptional profiling of primary monocyte derived macrophages (MDMs) comparing control untreated MDMs with MDMs exposed with Serotype 2 Streptococcus pneumoniae (D39) strain (MOI 10) for 3 hours) Three-condition experiment, control MDMs vs. D39 infected MDMs vs Stop infected MDMs. Biological replicates: 3 control replicates, 3 infected D39 replicates and 3 infected penumolysin deficient (STOP) MOI 10.

2021-03-01 | E-MTAB-9055 | biostudies-arrayexpress

N-acetylgalactosamine Mediated Regulation of the aga Operon by AgaR in Streptococcus pneumoniae

Project description:Three Microarray comparisons have been preformed in this study. 1- Transcriptome comparison of the Streptococcus pneumoniae D39 wild type grown in M17 medium + 0.5 % (w/v) NAGa (NAGaM17) to M17 medium + 0.5 % (w/v) glucose (GM17) (GSM2372597 and GSM2372598). 2- Transcriptome comparison of the Streptococcus pneumoniae D39 ΔagaR to D39 wild type grown in M17 medium + 0.5 % (w/v) glucose (GM17) (GSM2372599 and GSM2372600). 3- Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild type grown in M17 medium + 0.5 % (w/v) NAGa (NAGaM17) (GSM2290636 and GSM2290637).

2016-11-02 | GSE86008 | GEO

Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Glucose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

2015-03-06 | GSE66558 | GEO

Impact of bguR delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Glucose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔbguR to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

2013-02-20 | GSE43342 | GEO

Impact of rokA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Glucose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔrokA to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

2012-10-22 | GSE41448 | GEO

Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of sialic acid

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild-type grown in M17 medium + 0.5% sialic acid (SM17).

2015-03-06 | GSE66559 | GEO

Impact of nanR delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of sialic acid

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔnanR to D39 wild-type grown in M17 medium + 0.5% sialic acid (SM17).

2015-03-06 | GSE66535 | GEO

Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presece of N-acetylglucosamine (NAG)

Project description:Transcriptome comparision of the Streptococcus pneumoniae D39 ccpA mutant to D39 wild-type grown in CDM + 0.5 % N-acetylglucosamine (NAG)

2017-01-12 | GSE89590 | GEO

Impact of celR delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Cellobiose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔcelR to D39 wild-type grown M17 medium + 0.5 % (w/v) Cellobiose (CM17).

2011-07-25 | GSE30891 | GEO

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