Estrogen receptor alpha ChIP-seq in p53 null mouse mammary gland

ABSTRACT: ERα is a major driver for breast cancer initiation and progression.However,the fundamental mechanisms,including global cistromic and genomic transcriptional responses that are required to elicit breast cancer initiation and progression in response to ERα, have not been elucidated. We used chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) to identify estrogen regulated genes that directly recruit ERα in the p53 null mouse mammary gland

ORGANISM(S): Mus musculus

PROVIDER: GSE77977 | GEO | 2022/02/06

REPOSITORIES: GEO