Expression changes in lymphoid cells on excision of Runx1

ABSTRACT: The Runx genes function as dominant oncogenes that collaborate potently with Myc or loss of p53 to induce lymphoma when over-expressed. Here we examined the gene changes in an Eµ-Myc model of Burkitt’s lymphoma on deletion of Runx1, and found a gene signature that was associated with lymphoid proliferation, survival and differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE78001 | GEO | 2016/02/18

SECONDARY ACCESSION(S): PRJNA312340

REPOSITORIES: GEO