The role of subclonal population of cells on tumor growth

ABSTRACT: In this study we activated subclonal differentiation in pancreatic adenocarcinoma cells to study the role of differentiated cells on tumor growth. Mesenchymal pancreatic adenocarcinoma (MiaPaCa) cells differentiated into adipose and endothelial cells to assess the tumor initiation potential of the differentiated cells and molecular changes associated with cell differentiation. Epithelial (TC-2742-2) cells expressed with Ebf2 were analyzed for its tumorigenic potential and molecular changes associated with Ebf2 expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE78014 | GEO | 2016/05/01

SECONDARY ACCESSION(S): PRJNA312359

REPOSITORIES: GEO