Dataset Information


Single cell transcriptomic profiling of mouse pancreatic progenitors

ABSTRACT: We report the transcriptome of single pancreatic cells at embryonic day e13.5 Overall design: Single cells mRNA of wild-type mouse pancreata at embryonic day 13.5

INSTRUMENT(S): Illumina HiSeq 2500 (Mus musculus)

SUBMITTER: Diana Elena Stanescu  

PROVIDER: GSE78510 | GEO | 2016-12-27



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Single cell transcriptomic profiling of mouse pancreatic progenitors.

Stanescu Diana E DE   Yu Reynold R   Won Kyoung-Jae KJ   Stoffers Doris A DA  

Physiological genomics 20161223 2

The heterogeneity of the developing pancreatic epithelium and low abundance of endocrine progenitors limit the information derived from traditional expression studies. To identify genes that characterize early developmental tissues composed of multiple progenitor lineages, we applied single-cell RNA-Seq to embryonic day (e)13.5 mouse pancreata and performed integrative analysis with single cell data from mature pancreas. We identified subpopulations expressing macrophage or endothelial markers a  ...[more]

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