BRD4 represses CBX5

ABSTRACT: BRD4 is amplified and/or up-regiulated in a subset of ovarian cancer which correlates with a poor survival siRNA sensitization screens in the presence of CHK1 inhibitor, LY2606368, identify BRD4 as a therapeutic target in ovarian cancer. BRD4 suppression by either siRNA or using JQ1 increases CBX5 expression

ORGANISM(S): Homo sapiens

PROVIDER: GSE78704 | GEO | 2016/05/01

SECONDARY ACCESSION(S): PRJNA313265

REPOSITORIES: GEO