Transcriptomics

Dataset Information

0

Characterisation of Transcriptional Changes in the Spinal Cord of the Progressive Experimental Autoimmune Encephalomyelitis ABH Mouse Model by RNA Sequencing


ABSTRACT: RNA sequencing was used to explore global gene expression in the chronic relapsing and secondary progressive EAE (pEAE) Biozzi ABH mouse model of MS. Spinal cord tissue RNA from pEAE Biozzi ABH mice and healthy littermate controls was sequenced. 2,072 genes were differentially expressed (q<0.05) from which 1,397 were significantly upregulated and 675 were significantly downregulated. This hypothesis-free investigation characterised the genomic changes that describe the pEAE mouse model.

ORGANISM(S): Mus musculus

PROVIDER: GSE78996 | GEO | 2016/07/01

SECONDARY ACCESSION(S): PRJNA314610

REPOSITORIES: GEO

Similar Datasets

2016-07-01 | E-GEOD-78996 | biostudies-arrayexpress
2007-05-15 | E-MEXP-1025 | biostudies-arrayexpress
2016-07-08 | PXD001011 | Pride
2013-09-09 | E-GEOD-47486 | biostudies-arrayexpress
2021-04-30 | GSE130177 | GEO
2023-05-11 | GSE231833 | GEO
2019-02-25 | PXD011428 | Pride
2022-03-01 | GSE190289 | GEO
2021-04-15 | GSE172083 | GEO
2013-09-09 | GSE47486 | GEO