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Determine the function of lncBATE10 in brown and white adipocyte culture

ABSTRACT: Purpose: Determine the function of lncBATE10 in brown and white adipocyte differentiation Methods: primary brown and white apreadipocytes were isolated by cell culture. We infected brown preadipocytes with retroviral shRNA targeting lncBATE10 or with retrovirus overexpressing lncBATE10. Cells were induced to differetinate for 5 days. Total RNA were harvested for RNA-seq Conclusions: Our study shows that lncBATE10 is required for BAT-selective program expression. Overexpression of lncBATE10 is not sufficient to promote BAT marker expression.

ORGANISM(S): Mus musculus

PROVIDER: GSE79169 | GEO | 2017/08/01

SECONDARY ACCESSION(S): PRJNA317337

REPOSITORIES: GEO

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