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Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors

ABSTRACT: Tumor touch imprints (TTIs) are routinely used for the molecular diagnosis of neuroblastomas by interphase fluorescence in-situ hybridization (I-FISH). However, to enable an up-to-date molecular diagnosis of neuroblastomas and to identify new markers to refine risk and therapy stratification methods, whole genome approaches are demanded. We tested whether an ultra-high density SNP array platform identifying copy number changes of varying sizes down to few exons can be applied to detect genomic changes on DNA extracted from TTIs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE79187 | GEO | 2016/08/31

SECONDARY ACCESSION(S): PRJNA315129

REPOSITORIES: GEO

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