Genomics

Dataset Information

34

Expression data of cultured bovine granulosa cells plated at different initial cell densities


ABSTRACT: In previous studies it has been shown that bovine granulosa cells (GC) cultured at a high plating density dramatically change their physiological and molecular characteristics, thus resembling an early stage of luteinization. During the present study, these specific effects on the GC transcriptome were comprehensively analysed of the same cell culture model comparing GC cultured at normal and high density. Overall design: Granulosa cells cultured at different plating densities (normal and high; 3 replicates each) were used and processed for microarray analysis

INSTRUMENT(S): [BovGene-1_0-st] Bovine Gene 1.0 ST Array [transcript (gene) version]

SUBMITTER: Jens Vanselow  

PROVIDER: GSE79311 | GEO | 2016-12-31

SECONDARY ACCESSION(S): PRJNA315443

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE79311_RAW.tar Raw
GSE79311_normalized_matrix.txt.gz Txt
filelist.txt Txt
Items per page:
1 - 3 of 3
altmetric image

Publications

Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density.

Baufeld Anja A   Koczan Dirk D   Vanselow Jens J  

Reproductive biology and endocrinology : RB&E 20170105 1


<h4>Background</h4>In previous studies it has been shown that bovine granulosa cells (GC) cultured at a high plating density dramatically change their physiological and molecular characteristics, thus resembling an early stage of luteinization. During the present study, these specific effects on the GC transcriptome were comprehensively analysed to clarify the underlying mechanisms.<h4>Methods</h4>GC were cultured in serum free medium with FSH and IGF-1 stimulation at different initial plating d  ...[more]

Similar Datasets

2017-01-01 | S-EPMC5217602 | BioStudies
2018-01-01 | S-EPMC6090175 | BioStudies
2014-01-01 | S-EPMC4085383 | BioStudies
2009-01-01 | S-EPMC2847890 | BioStudies
2017-01-01 | S-EPMC5670713 | BioStudies
2019-03-07 | PXD010658 | Pride
1000-01-01 | S-EPMC5397658 | BioStudies
2018-01-01 | S-EPMC5805282 | BioStudies
2016-01-01 | S-EPMC4939739 | BioStudies
2020-01-01 | S-EPMC7511402 | BioStudies