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DNA methylation data from human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast

ABSTRACT: Here we report the derivation of human parthenogenetic haploid ESCs which contain only one set of chromosome. These two cell lines, which we designated hPGES1 and hPGES2, show conventional ESCs and parthenogenetic-derived DNA methylation state.

ORGANISM(S): Homo sapiens

PROVIDER: GSE80226 | GEO | 2016/07/13

SECONDARY ACCESSION(S): PRJNA318353

REPOSITORIES: GEO

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mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast

Project description:Here we report the derivation of human haploid ESCs from parthenogenetic haploid embryos. We used RNA-seq to compare the gene expression levels among human parthenogenetic haploid ESCs (hPGES), normal human ESCs (H9) and human forskin fibroblasts and identified that these cells express conventional ESCs pluripotent markers and most maternally imprinted genes were down-regulated.

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mRNA expression data from monkey PG-haESCs, ICSI-derived ESCs and somatic fibroblasts

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