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Transcriptional effect of ETV1 knockdown in melanoma cells

ABSTRACT: ETV1 is amplified in a subset of melanomas. Here, we performed RNA-seq on two BRAF V600E mutant melonoma cell lines transduced with a scrambed shRNA and two individual ETV1 shRNA

ORGANISM(S): Homo sapiens

PROVIDER: GSE80352 | GEO | 2018/04/15

REPOSITORIES: GEO

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Comparing gene expression profiles of pigmented and amelanotic (MPNST-like) melanomas arising in the genetically engineered BRAF(V600E)-Cdk4(R24C) mouse melanoma model

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Gene expression profile of ETV1 knockdown in LNCaP prostate cancer cells

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Project description:ETV1 is highly expressed in GIST cells and required for their survival and growth. To identify genes and pathways regulated by ETV1 in GIST, we performed expression profiles of GIST cells after ETV1 knockdown. Two GIST cell lines (GIST48 and GIST882) were infected in duplicate with three shRNA viruses (Scrambled, ETV1sh1-B11TRCN0000013923, ETV1sh2-TRCN0000013925). Four days after infection, RNA was harvested for expression profiling.

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Gene expression profile of ETV1 knockdown in LNCaP prostate cancer cells

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ETV1 knockdown in GIST cell lines

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