Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE80961 | GEO | 2017/02/07

SECONDARY ACCESSION(S): PRJNA320124

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis.

Project description: Not available

| S-EPMC5034609 | biostudies-literature

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis (RRBS)

Project description:We depicted a genome-wide integrative view of DNA methylome by reduced representation bisulfite sequencing (RRBS) and transcriptome by RNA-seq during brown and white adipocyte differentiation. Our analysis demonstrated that DNA methylation is a stable epigenetic signature for brown and white cell lineage before, during and after differentiation. When comparing white to brown adipocytes at all three time points of differentiation, we identified five members of the Hox family whose expression levels were anti-correlated with promoter methylation, suggesting a regulatory role of DNA methylation in transcription.

2017-02-07 | GSE80959 | GEO

Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis (RNA-Seq)

2017-02-07 | GSE80960 | GEO