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Genome-wide gene expression analysis of WERI-Rb-1 (retinal cells) infected with Toxoplasma gondii over time

ABSTRACT: Analysis of gene expression patterms following infection of the parasite Toxoplasma gondii in a clinically relevant retinal cell line over a time course of 2 hours, 6 hours and 24 hours. Parasites were washed off after 2 hours to ensure that gene expression changes are truly reflective of an on-going infection, and not on-going parasite invasion.

ORGANISM(S): Homo sapiens

PROVIDER: GSE81016 | GEO | 2016/05/03

SECONDARY ACCESSION(S): PRJNA320290

REPOSITORIES: GEO

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Genome-wide DNA methylation analysis of WERI-Rb-1 (retinal cells) infected with Toxoplasma gondii over time

Project description:Analysis of DNA methylation patterns following infection of the parasite Toxoplasma gondii in a clinically relevant retinal cell line over a time course of 2 hours, 6 hours and 24 hours. Parasites were washed off after 2 hours to ensure that methylation changes are truly reflective of an on-going infection, and not on-going parasite invasion.

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Genome-wide gene expression analysis of human foreskin fibroblast cells infected with Toxoplasma gondii over time

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ATAC-seq Identification of Chromatin Accessibility in Both Human Host Cells and the Parasite Toxoplasma gondii

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Project description:Infection of RAW264.7 cells for 24 hours with 32 Toxoplasma Progeny from a Type II x Type III cross To measure changes in gene expression induced in macropahges upon Toxoplasma infection, we infected RAW 264.7 macrophages in cell culture with one of 32 Toxoplasma parasite progeny from a Type II x Type III cross. RNA was harvested 24 hours post infection.

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