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DNase Hypersensitivity Peaks from Rat Schwann Cells

ABSTRACT: We utilized DNase-Seq to identify open chromatin regions within Schwann cells. This data was used in conjunction with sequence conservation and transcription factor binding site prediction to identify putative cis-regulatory elements critical for Schwann cells. We used three independent biological replicates, and for our studies used sample 'barcode4' as a representative sample for all three. DNase HSS peaks were identified using F-Seq and HOMER, and overlapped to prioritize candidate regions. These regions were then verified using luciferase assays.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE81669 | GEO | 2017/08/24

SECONDARY ACCESSION(S): PRJNA322264

REPOSITORIES: GEO

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