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Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2

ABSTRACT: Neural crest cells are a transient embryonic population, hence are neither present after bith and nor are they readily accesible for analysis. Therefore, little is known about the genetic networks that regulate NC especification, delamitation and migration from the dorsal neural tube to their final destination along the embryo. Here we have developed a novel resource for lineage tracing and for the isolation of neural crest cells in the chick embryo, enabling us to perform a genome-wide expression screen in neural crest progenitors versus neuroepithelial cells.

ORGANISM(S): Gallus gallus

PROVIDER: GSE81717 | GEO | 2016/05/21

SECONDARY ACCESSION(S): PRJNA322350

REPOSITORIES: GEO

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