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Gene expression signatures for TCM Suduxing treated HepG2.2.15 cells compared to Suduxing untreated HepG2.2.15 cells

ABSTRACT: To further analyze the gene expression profile regulated by TCM Suduxing, we employed whole genome microarray expression profiling as a discovery platform to identify the differentially expressed genes. Human hepatocellular carcinoma cell lines HepG2.2.15 cells were treated for 48 hr with 0.001 μg/ml and 0.01μg/ml Suduxing or without Suduxing(control samples) in vitro. The differentially expressed genes including all detected and normalized signal more than 8 were selected and 538 upregulated- and downregulated- genes were identified between 0.01μg/ml dose and control samples.Afterwards, the differentially-expressed genes were analyzed using KEGG database (http://www.genome.jp/kegg/) and 10 genes related to HBV infection-related molecular interaction network were identified.

ORGANISM(S): Homo sapiens

PROVIDER: GSE81835 | GEO | 2017/05/24

SECONDARY ACCESSION(S): PRJNA322672

REPOSITORIES: GEO

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