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IL-18 nAbs block deleterious inflammatory cytokines induced by acute β-AR stimulation in heart


ABSTRACT: To directly test whether inhibition of IL-18 by IL-18 neutralizing monoclonal antibodies (IL-18 nAbs) is sufficient for blocking the inflammatory responses of heart caused by acute β-adrenergic insult, mice were subjected to intraperitoneal injection with rat IL-18 nAbs or IgG as a negative control 1hr after isoproterenol treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE82034 | GEO | 2016/05/31

SECONDARY ACCESSION(S): PRJNA323726

REPOSITORIES: GEO

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