Transcriptomics

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Role of IgD in B cell anergy


ABSTRACT: To define the global landscape of mRNA changes in anergic B cells, and how this affected by surface IgD, mature CD93-CD23+ HEL-binding B cells were sorted from spleens of independent transgenic mice of the following genotypes: MD4, naïve B cells coexpressing IgM and IgD; MD4:ML5, anergic B cells coexpressing IgM and IgD; MM4, naive B cells expressing only IgM; MM4:ML5, anergic B cells expressing only IgM; DD6, naive B cells expressing only IgD; DD6:ML5, anergic B cells expressing only IgD.

ORGANISM(S): Mus musculus

PROVIDER: GSE82091 | GEO | 2016/09/30

SECONDARY ACCESSION(S): PRJNA323990

REPOSITORIES: GEO

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