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Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

ABSTRACT: We isolated RNAs from Otp-lineage cells in the mouse brain using translating ribosome affinity purification (TRAP) approach. We compared two groups of mice: Otp-cre; ROSAfsTRAP (control) and Otp-cre; Cicf/f; ROSAfsTRAP (conditional knockout). Following RNA isolation, RNAseq was performed and gene expression profiles were compared between controls and conditional knockouts.

ORGANISM(S): Mus musculus

PROVIDER: GSE83243 | GEO | 2017/01/31

SECONDARY ACCESSION(S): PRJNA325369

REPOSITORIES: GEO

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