Genomics

Dataset Information

0

Small RNA and mRNA transcriptome profiling in wildtype mice at multiple stages of spermatogenesis, from whole testis at day 1 postpartum (pp), day 3 pp, and day 7 pp and purified leptotene/zygotene and pachytene spermatocytes.


ABSTRACT: MicroRNAs are essential for spermatogenesis. However, the stage‑specific requirements for specific miRNAs in the male mammalian germ line remain largely uncharacterized. The miR‑34 family is, to date, the only miRNA proven to be necessary for the production of sperm in mice, though its germline roles are poorly understood. Here, we generate and analyze paired small RNA and mRNA profiles across different stages of germline development in male mice, focusing on time points shortly before and during meiotic prophase I.

ORGANISM(S): Mus musculus

PROVIDER: GSE83264 | GEO | 2016/09/01

SECONDARY ACCESSION(S): PRJNA325455

REPOSITORIES: GEO

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