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MiR-130b drives activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma by directly targeting Arhgap1

ABSTRACT: Analysis of miR-130b regulated genes in TC71 Ewing Sarcoma cells. The hypothesis tested being that overexpression of miR-130b increases metastasis in Ewing Sarcoma.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83548 | GEO | 2016/06/21

SECONDARY ACCESSION(S): PRJNA326311

REPOSITORIES: GEO

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miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma.

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