IFN-γ and IL-4 regulate epigenetic modifiers in macrophages

ABSTRACT: Interferon-γ (IFN-γ) or interleukin-4 (IL-4) prime macrophages towards classical (M1) or alternative (M2) activation, respectively. How IFN-γ and IL-4 prime epigenetic responses by altering expression of histone modifying enzymes and how this affects M1/M2 polarization is incompletely understood.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83957 | GEO | 2017/01/15

SECONDARY ACCESSION(S): PRJNA327558

REPOSITORIES: GEO