Genomics

Dataset Information

0

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation


ABSTRACT: Here we have characterized the role of KDM5 family during adipocyte differentiation of 3T3-L1 preadipocytes. Notably, our study represents the first to simultaneously knock down all the KDM5 family members thereby avoiding interference from redundancy between KDM5 subtypes. Using a combination of knockdown and genome-wide ChIP-seq and RNA-seq analyses we uncover the underlying mechanisms of the inhibition of adipogenesis as well as basic aspects of KDM5 function.

ORGANISM(S): Mus musculus

PROVIDER: GSE84410 | GEO | 2016/12/01

SECONDARY ACCESSION(S): PRJNA329107

REPOSITORIES: GEO

Similar Datasets

2018-07-03 | GSE108502 | GEO
2024-03-04 | GSE239950 | GEO
2018-01-16 | GSE94058 | GEO
2016-04-05 | E-GEOD-78206 | biostudies-arrayexpress
2011-04-01 | E-GEOD-21157 | biostudies-arrayexpress
2012-09-05 | E-GEOD-40565 | biostudies-arrayexpress
2023-06-07 | GSE233707 | GEO
2021-03-16 | GSE156010 | GEO
2015-12-22 | E-GEOD-70589 | biostudies-arrayexpress
2016-04-05 | GSE78206 | GEO