Transcriptomics

Dataset Information

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Non-replicative persistence of M. tuberculosis under iron starvation


ABSTRACT: Iron restriction is a growth limiting condition encountered by M. tuberculosis in the host. In this study we examined the survival and physiology of iron depleted M. tuberculosis. We found that iron depleted M. tuberculosis survive for long time with little or no replication and is able to resume normal growth when iron becomes available. To understand the mechanism used by M. tuberculosis to survive under iron starvation we examine the transcriptional profile of iron-starving in comparison to that of iron-sufficient M. tuberculosis.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE84554 | GEO | 2017/09/15

SECONDARY ACCESSION(S): PRJNA329603

REPOSITORIES: GEO

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