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Integrated analyses identify phenotype specific BMP4 signaling in breast cancer [RNA-seq]

ABSTRACT: Bone morphogenetic protein 4 (BMP4) plays an important role in cancer pathogenesis. In breast cancer, it reduces proliferation and increases migration in a cell line-dependent manner. To characterize the transcriptional mediators of these phenotypes, we performed RNA-seq and DNase-seq analyses after BMP4 treatment in MDA-MB-231 and T-47D breast cancer cells that respond to BMP4 with enhanced migration and decreased cell growth, respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84577 | GEO | 2016/12/12

SECONDARY ACCESSION(S): PRJNA329672

REPOSITORIES: GEO

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