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Gene expression data from MGH-U3 following FGFR3 knock-down using FGFR3 siRNAs

ABSTRACT: To better understand the molecular mechanisms underlying altered-FGFR3 oncogenic activity in bladder carcinomas, we made use of MGH-U3 cell lines, which were derived from a human bladder tumor and endogenously expressed a mutated activated form of FGFR3 (FGFR3-Y375C), the growth and transformation of these cell lines being dependent on activated-FGFR3 activity. We conducted a gene expression analysis using Affymetrix DNA arrays in this cell line treated or not with FGFR3 siRNAs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84731 | GEO | 2018/02/16

REPOSITORIES: GEO

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