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L1CAM knockdown significantly reduces metastasis in a xenograft model of human melanoma

ABSTRACT: As L1CAM expression is associated with metastasis in melanoma patients, it could be a target for the combination therapies. We investigated the functional role of L1CAM in melanoma metastasis by the use of a xenograft model of human melanoma in mice using RNAi mediated L1CAM knockdown melanoma cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84864 | GEO | 2016/07/27

SECONDARY ACCESSION(S): PRJNA335392

REPOSITORIES: GEO

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