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Effect of from Human Umbilical Vein Endothelial Cells

ABSTRACT: We profiled global gene expression in primary human umbilical vein endothelial cells to determine the gene expression changes associated with knocking down PKM2 and p53. We identified a p53 dependent transcriptional response that remodels metabolism in cells lacking p53, thus limiting cell growth.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84877 | GEO | 2016/07/27

SECONDARY ACCESSION(S): PRJNA335410

REPOSITORIES: GEO

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Effect of from Human Umbilical Vein Endothelial Cells

Project description:We profiled global gene expression in primary human umbilical vein endothelial cells to determine the gene expression changes associated with knocking down PKM2 and p53. We identified a p53 dependent transcriptional response that remodels metabolism in cells lacking p53, thus limiting cell growth. Human Umbilical Vein Endothelial Cells were transfected with siRNA duplexes targeting PKM2 and / or p53, RNA was extracted and subjected to RNA sequencing

2016-07-27 | E-GEOD-84877 | biostudies-arrayexpress

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MicroRNA expression profile of human umbilical vein endothelial cells treated with Angiogenin (ANG)

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ChIP-seq from endothelial cell of umbilical vein (ENCSR000ALG)

Project description:Control ChIP-seq on human endothelial cell of umbilical vein For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

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Secretome analysis of Human Umbilical Vein Endothelial Cells with PMA treatment using gel-LC-MS/MS

Project description:Secretome analysis of Human Umbilical Vein Endothelial Cells with PMA treatment using gel-LC-MS/MS

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Expression profiling in Human Umbilical Vein Endothelial Cells (HUVEC)

Project description:Whole transcriptome gene expression profiling of Normal -(HUVEC) Human Umbilical Vein Endothelial Cells The HUVEC gene expression results analyzed in this study are further described in Kustermann S. et al. (2014) A real-time impedance based screening assay for drug induced vascular leakage.

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long read RNA-seq from endothelial cell of umbilical vein (ENCSR687RWI)

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