Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85108 | GEO | 2016/12/10

SECONDARY ACCESSION(S): PRJNA336182

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions.

Project description: Not available

| S-EPMC5159541 | biostudies-literature

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions [ChIP-seq]

Project description:In our work we used high-throughput sequencing methods to get insight in the role of CTCF in ER-mediated gene regulation in luminal breast cancer cells. After assessing genome-wide binding of CTCF, ER, FOXA1 and Lamin B in MCF7 cells treated with estrogen for different time points, we could correlate the interaction to the chromatin with estrogen-induced de novo transcription (from GRO-seq data) and loop formation (from ChIA-PET, Fullwood et al., 2009). We observed that CTCF binding correlates with ER-mediated transcription and its depletion can affect ER-ER loop formation and subsequently gene expression.

2016-12-10 | GSE85106 | GEO

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions [RNA-seq]

2016-12-10 | GSE85088 | GEO

CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions

Project description:CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions

| PRJNA336182 | ENA

HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors.

Project description: Not available

| S-EPMC2169410 | biostudies-literature

p150/glued modifies nuclear estrogen receptor function.

Project description: Not available

| S-EPMC2675952 | biostudies-literature

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

Project description: Not available

| S-EPMC394449 | biostudies-other

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Project description: Not available

| S-EPMC5540176 | biostudies-literature

TRIM28 modulates nuclear receptor signaling to regulate uterine function

Project description:This project identified that TRIM28 can modulate progesterone and estrogen signaling in both human and mouse endometrium to regulate its normal functions during pregnancy. TRIM28 showed proximal localization and co-immunoprecipitation with PR and ERalpha. The ablation of TRIM28 can inhibit the chromatin binding activity of PR and ERalpha leading to disrupted estrogen and progesterone signaling. This immunoprecipitation using TRIM28 antibody was performed in pre-decidual human endometrial stromal cells (HESCs) without any hormone treatment. The potential interacting proteins of TRIM28 was analyzed using mass spec.

2023-07-05 | MSV000092346 | MassIVE

Predictive features of ligand-specific signaling through the estrogen receptor.

Project description: Not available

| S-EPMC4848761 | biostudies-literature