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Expression of oxysterol pathway genes in estrogen positive breast carcinomas-second phase

ABSTRACT: Metabolism of anticancer drugs markedly affects their antitumor effects. The major goal of our study was to investigate associations of gene expression of enzymes metabolizing taxanes and/or anthracyclines with therapy response and survival of breast carcinoma patients The present study investigated transcript levels of key modulators of oxysterol signaling pathway, including oxysterol receptors, metabolic enzymes and transporters in the group of hormone-receptor positive breast carcinoma patients to evaluated potential clinical significance of these genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85206 | GEO | 2017/04/06

SECONDARY ACCESSION(S): PRJNA336555

REPOSITORIES: GEO

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