Generation of intestinal progenitor cells from mouse fibroblasts
Ontology highlight
ABSTRACT: We show direct conversion of mouse fibroblasts to cells that closely resemble intestinal stem cells (ISCs), through the state of fetal-type progenitor cells, called FIPCs. The induced ISCs (iISCs) exhibit self-renewal capacity and intestinal multi-lineage differentiation potential. Upon transplantation, iFIPCs and iISCs reconstitute colonic and intestinal epithelia, respectively.
ORGANISM(S):  Mus musculus 
PROVIDER: GSE85232 | GEO | 2017/09/22 
SECONDARY ACCESSION(S): PRJNA337910
REPOSITORIES:  GEO
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