Transcriptomics,Genomics

Dataset Information

25

Pax5 drives the metabolic shift in the development of pB-ALL as a result of BCR/ABLp190 susceptibility


ABSTRACT: We used microarrays to investigate gene expression changes in tumor-bearing Sca1-BCR/ABLp190 and Sca1-BCR/ABLp190+Pax5+/- mice. We also analyze gene expression changes in preleukemic Sca1-BCR/ABLp190 and Sca1-BCR/ABLp190+Pax5+/- mice Overall design: Tumor-bearing bone marrows of seven Sca1-BCR/ABLp190+Pax5+/- and two Sca1-BCR/ABLp190 mice compared with B220+ bone marrow B cells from five WT mice. Preleukemic proB and preB cells of bone marrows of three Sca1-BCR/ABLp190+Pax5+/- and three Sca1-BCR/ABLp190 mice compared with proB and preB cells of bone marrows of three WT mice

INSTRUMENT(S): [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

SUBMITTER: Isidro Sánchez García  

PROVIDER: GSE85600 | GEO | 2016-08-16

SECONDARY ACCESSION(S): PRJNA338921

REPOSITORIES: GEO

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