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Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [ChIP-Seq]

ABSTRACT: Heterozygous mutations in GATA4 cause congenital heart defects and cardiomyopathy through unknown mechanisms. To gain insights into the genome-wide localization perturbations during human cardiac development due to GATA4 heterozygosity, we performed ChIP-seq of wildtype and GATA4-G296S diseased cardiomyocytes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85628 | GEO | 2016/12/15

SECONDARY ACCESSION(S): PRJNA339028

REPOSITORIES: GEO

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