Transcriptomics

Dataset Information

30

Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with CLA


ABSTRACT: Trans-10, Cis-12 conjugated linoleic acid (t10c12 CLA) causes fat loss in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to t10c12 CLA. Their gene expression responses between 4 to 24 hr after treatment showed a common set of early gene expression changes indicative of an integrated stress response (ISR). Keywords: control/treatment time course Overall design: Mouse 3T3-L1 RNA for each time point was isolated from control and treatment samples for analysis on microarrays with two to four biological reps.

REANALYSED by: GSE119128

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

ORGANISM(S): Mus musculus  

SUBMITTER: Jean-Jack M. Riethoven  

PROVIDER: GSE8681 | GEO | 2008-01-11

SECONDARY ACCESSION(S): PRJNA109033

REPOSITORIES: GEO

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