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Loss of miR-16 mediated silencing of SQSTM1 is associated with Paget's associated osteosarcoma

ABSTRACT: We report an upregulation of miR-16 in Paget's disease of bone which is to target the SQSTM1. When miR-16 is lost in Paget's disease, there is malignant transformation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE87018 | GEO | 2017/04/18

SECONDARY ACCESSION(S): PRJNA343232

REPOSITORIES: GEO

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