Complete atrio-ventricular canal defects in mouse hearts lacking G-protein receptor kinases

ABSTRACT: Combined ablation of all 3 cardiac-expressed GRKs in the developing mouse heart impaired Hedgehog/Smoothened and GATA signaling, recapitulating heart abnormalities of human Complete Atrioventricular Septal Defect.

ORGANISM(S): Mus musculus

PROVIDER: GSE87321 | GEO | 2017/09/30

SECONDARY ACCESSION(S): PRJNA344339

REPOSITORIES: GEO