Transcriptomics,Genomics

Dataset Information

21

Implication of an Immune Score in Molecular Subtypes and Distant Metastasis of Breast Cancer: Comparison between Western and Chinese Han Patients


ABSTRACT: Seventy-one breast cancer patients with stages II and III breast cancer were included. They received four preoperative cycles of a weekly PCb (paclitaxel plus carboplatin) regimen. The purpose of this study was to examine the predictive value of the ER pathway for a response to chemotherapy using a gene microarray method. In addition, this study aimed to identify novel ER-related genes, which, combined with ER levels, would provide a robust multi-variable prediction of patient outcome to chemotherapy. Overall design: Biopsy tissue was taken from patients received neoadjuvant chemotherapy. They received four preoperative cycles of a weekly PCb (paclitaxel plus carboplatin) regimen. The arrays were washed and stained according to the Affymetrix protocol (EukGE-WS2v4) using a GeneChip Fluidics Station 450 (Affymetrix). The arrays were scanned with the GeneChip Scanner 3000 (Affymetrix).

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

SUBMITTER: Jeff Chou  

PROVIDER: GSE87377 | GEO | 2016-10-10

SECONDARY ACCESSION(S): PRJNA344563

REPOSITORIES: GEO

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