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Low H3K27me3 define poorly prognostic pediatric posterior fossa ependymomas

ABSTRACT: A subgroup of Posterior fossa ependymomas show reduced H3K27me3 are more invasive, exhibit poor prognosis and epigenetically deregulated genes converge on radial glial factors, suggesting developing cerebellar radial glia as candidate cells-of-origin.

ORGANISM(S): Homo sapiens

PROVIDER: GSE89451 | GEO | 2016/11/23

SECONDARY ACCESSION(S): PRJNA352239

REPOSITORIES: GEO

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Project description:This SuperSeries is composed of the SubSeries listed below.

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Epigenomic Alterations Define Lethal CIMP positive Ependymomas of Infancy

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