Genomics

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Genomic imbalances of lung cancer


ABSTRACT: The array comparative genomic hybridization (aCGH) was perform to identify regions with genomic imbalance in lung cancer.The aCGH analysis detected a total of 325 regions with genomic imbalance in all 8 lung cancer samples, ranging from focal rearrangements (70 kb–5 Mb) to chromosome-arm alterations with chromosomal segments amplification or deletion. Among these mutations, a total of 115 genomic imbalances were discovered occurring at high frequency varying from 25% to 50%.

ORGANISM(S): Homo sapiens

PROVIDER: GSE89927 | GEO | 2016/11/17

SECONDARY ACCESSION(S): PRJNA354298

REPOSITORIES: GEO

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