Genomics

Dataset Information

32

Genomic imbalances of lung cancer


ABSTRACT: The array comparative genomic hybridization (aCGH) was perform to identify regions with genomic imbalance in lung cancer.The aCGH analysis detected a total of 325 regions with genomic imbalance in all 8 lung cancer samples, ranging from focal rearrangements (70 kb–5 Mb) to chromosome-arm alterations with chromosomal segments amplification or deletion. Among these mutations, a total of 115 genomic imbalances were discovered occurring at high frequency varying from 25% to 50%. Overall design: Genomic imbalances of lung cancer was tested in 8 randomly-selected pairs of lung cancer tissue and adjacent normal tissues using the Agilent SurePrint G3 human CGH 4×180K array by a commercial company

INSTRUMENT(S): Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Probe Name version)

SUBMITTER: Lei Yang  

PROVIDER: GSE89927 | GEO | 2016-11-17

SECONDARY ACCESSION(S): PRJNA354298

REPOSITORIES: GEO

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