Dataset Information


Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids II

ABSTRACT: We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Proof of principle transfection experiment. Pcdh7 (a gene identified as being a regulator of many genes) is transfected into A23 and HEK cells and compared to A23 and HEK cells transfected with an empty vector. Upregulated genes predicted by our approach are compared with the transfection experiments Keywords: tranfection, regulation of gene expression Overall design: There are 4 microarrays. The first two are biological replicates of A23 (transfected with Pcdh7, labeled with cy5) / A23 (tranfected with empty vector, labeled with cy3). The second two are biological replicates of HEK (transfected with Pcdh7, labeled with cy5) / HEK (tranfected with empty vector, labeled with cy3).

INSTRUMENT(S): Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)

SUBMITTER: Christopher Park 

PROVIDER: GSE9066 | GEO | 2008-03-13



Similar Datasets

2008-04-03 | E-GEOD-9066 | ArrayExpress
| GSE95856 | GEO
2015-11-03 | PXD002593 | Pride
2015-05-08 | E-GEOD-68668 | ArrayExpress
2008-06-16 | E-GEOD-8834 | ArrayExpress
2007-08-23 | GSE8834 | GEO
| GSE102821 | GEO
2013-11-21 | E-GEOD-52546 | ArrayExpress
2008-06-16 | E-GEOD-939 | ArrayExpress
| PRJNA129473 | ENA