Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of TPR50 Tau P301S Transgenic Mouse in different brain regions and time-points

ABSTRACT: Purpose: The goal of this study was to assess gene expression changes in TPR50 Tau transgenic mice. The mice was backcrossed with 2 divergent mouse strains - DBA and FVB along with the parent C57BL6 strain. The resulting F1 hybrids were used for further analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE90693 | GEO | 2018/08/28

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

microRNA-seq of TPR50 Tau P301S Transgenic Mouse in different brain regions and time-points

Project description:Purpose: The goal of this study was to assess miRNA expression changes in TPR50 Tau transgenic mice. The mice was backcrossed with 2 divergent mouse strains - DBA and FVB along with the parent C57BL6 strain. The resulting F1 hybrids were used for further analysis.

2018-08-28 | GSE89983 | GEO

Cdk5i peptide treatment in aged Tau P301S mice

Project description:To investigate the effects of Cdk5i peptide treatment on gene expression in cortical neurons that isolated from aged Tau P301S mice

2023-03-27 | GSE222327 | GEO

Tau-P301S sorted neurons and astrocytes

Project description:Tau-P301S sorted neurons and astrocytes

| PRJNA532847 | ENA

LncRNA/mRNA sequencing analysis on cerebral cortex of P301S mutant Tau transgenic mice (PS19).

Project description:Aggregation of the microtubule-associated protein, tau, can lead to neurofibrillary tangle formation in neurons and glia, the hallmark of tauopathy. The cellular damages induced by the tau overexpression and aggregation may lead to multiple pathologic features of tauopathy. However, the effect of aging on tauopathy has not been elucidated yet. Here, we conducted lncRNA/mRNA sequencing analysis on P301S mutant Tau transgenic mouse model (PS19) with different ages to track the genetic changes occurred by the aging and progression of tau overexpression.

2019-06-23 | GSE118473 | GEO

CNS cell-type specific gene profiling of aging P301S tau transgenic mice

Project description:RNA sequencing of cortex from young (3mo) and old (10mo) P301S tau transgenic mice

2019-01-01 | GSE118523 | GEO

(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 Thymus expression data

Project description:F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from normal tissues Keywords: Basal transcription profiles

2008-11-30 | GSE13227 | GEO

(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 spleen expression data

2008-11-30 | GSE13225 | GEO

(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 lung expression data

2008-11-30 | GSE13224 | GEO

(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 bone marrow expression data

2008-11-30 | GSE13223 | GEO

(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 blood expression data

2008-11-30 | GSE13222 | GEO