The intracellular mediators of the BMP pathway SMAD1/5 bind the Imprinting Control Regions through interaction with the ZFP57/KAP1 complex and contribute to maintain their DNA methylation and H3K9me3 in mouse embryonic stem cells

ABSTRACT: We report that SMAD1/5 bind the ICRs by interacting with the ZFP57/KAP1 complex and that this is necessary for the proper maintenance of methylation imprints in mESCs

ORGANISM(S): Mus musculus

PROVIDER: GSE90985 | GEO | 2017/12/07

SECONDARY ACCESSION(S): PRJNA356552

REPOSITORIES: GEO