Genomics

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MiRNA profiles associated with adynamic bone disease


ABSTRACT: Mineral and bone disorder (MBD) is observed universally in patients with chronic kidney disease (CKD). Detrimental MBD-related skeletal changes include increased prevalence of fracture, cardiovascular disease, and mortality. MicroRNAs (miRNAs) have been identified as useful biomarkers in various diseases, and the aim of this study was to identify miRNAs associated with parathyroid hormone level in peritoneal dialysis (PD) patients. The PD patients were enrolled and grouped by their intact parathyroid hormone (iPTH) levels. Of the patients, total RNA was extracted from whole blood samples (n=15) and underwent miRNA microarray analysis.

ORGANISM(S): Rattus norvegicus Mus musculus Homo sapiens

PROVIDER: GSE90991 | GEO | 2016/12/08

SECONDARY ACCESSION(S): PRJNA356607

REPOSITORIES: GEO

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