Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1

ABSTRACT: We analyzed anti-proliferative dominant-negative Brd4 mutants that compete with the function of distinct Brd4 domains. We used these Brd4 mutants to compare the Brd4-specific transcriptome with the transcriptome of JQ1 treated cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE92456 | GEO | 2017/06/09

SECONDARY ACCESSION(S): PRJNA357609

REPOSITORIES: GEO