Heterogeneity of hypothalamic Pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

ABSTRACT: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterised simply as direct targets for leptin, recent data suggest a more complex architecture. Using single cell RNA sequencing, we have generated an atlas of gene expression in murine POMC neurons, and compare the gene expression profiles of individual POMC-expressing neurons to assess the degree of heterogenity present in this cell population.

ORGANISM(S): Mus musculus

PROVIDER: GSE92707 | GEO | 2017/03/08

SECONDARY ACCESSION(S): PRJNA358404

REPOSITORIES: GEO