Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress

ABSTRACT: Exploring the mechanism of ethanol tolerance in Lactobacillus acetotolerans F28 and finding key genes which maybe participating in protecting cells from damage during ethanol stimulation.

ORGANISM(S): Lactobacillus acetotolerans

PROVIDER: GSE92732 | GEO | 2016/12/23

SECONDARY ACCESSION(S): PRJNA358482

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Ethanol stress response in Lactobacillus plantarum WCFS1

Project description:Transcriptome profiles of control Lactobacillus plantarum WCFS1 cells were compared with 8% ethanol adapted cells and with 10 min or 30 min 8% ethanol shocked cells.

2010-01-01 | GSE17847 | GEO

Ethanol stress response in Lactobacillus plantarum WCFS1

Project description:Transcriptome profiles of control Lactobacillus plantarum WCFS1 cells were compared with 8% ethanol adapted cells and with 10 min or 30 min 8% ethanol shocked cells. A continuous culture was performed in duplicate on medium containing ehtanol (tE). A shock experiment was performed in duplicate in which ethanol was added to a batch culture immediately after t0 (=control). The culture was sampled at time=0 (t0), time =10 min (t1) and time=30 min (t2).

2010-05-16 | E-GEOD-17847 | biostudies-arrayexpress

Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress.

Project description: Not available

| S-EPMC5453994 | biostudies-literature

Short- and long-term adaptation to ethanol stress and its cross-protective consequences in Lactobacillus plantarum.

Project description: Not available

| S-EPMC3147428 | biostudies-literature

Lactobacillus Membrane Vesicles

Project description:Bacterial membrane vesicles have been implicated in a broad range of functions in microbial communities from pathogenesis to gene transfer. Though first thought to be a phenomenon associated with Gram-negative bacteria, vesicle production in Staphylococcus aureus, Lactobacillus plantarum, and other Gram-positives has recently been described. Here we characterize MVs from three different Lactobacillus species (L. acidophilus, L. casei, and L. reuteri), determining that the size and protein composition of Lactobacillus-derived MVs have both similarities and differences with those produced by Gram-negative bacteria. Using proteomics, we identified more than 80 protein components from Lactobacillus-derived MVs, including some that were enriched in the vesicles themselves. For each species, vesicular proteins were categorized based on biological pathway and examined for subcellular localization signals in an effort to identify possible sorting mechanisms for MV proteins. Additionally, differences between MVs of other Lactobacillus species and Gram positive bacteria were highlighted. Information in this study will assist in elucidation of the formation and functions of MVs, as well as the development of therapeutic tools for vaccines, diagnosis, and therapeutic delivery.

2019-11-12 | PXD011278 | Pride

Short term exposure to alcohol induces transcriptional changes in non-tumorigenic breast cells

Project description:Breast cancer is the second leading cause of cancer-related deaths in women (*). Many genetic and behavioral risk factors can contribute to the initiation and progression of breast cancer, one being alcohol consumption. Numerous epidemiological studies have established a positive correlation between alcohol consumption and breast cancer; however, the molecular basis for this link remains ill defined. Elucidating ethanol-induced changes to global transcriptional programming in breast cells is important to ultimately understand how alcohol and breast cancer are connected mechanistically. We investigated early induced transcriptional changes in response to cellular exposure to moderate levels of alcohol. We treated the non-tumorigenic breast cell line MCF10A, and the tumorigenic breast cell lines MDA-MB-231 and MCF7, with ethanol for 6 h, then captured the changes to ongoing transcription using 4-thiouridine metabolic labeling followed by deep sequencing. Only the MCF10A cell line exhibited statistically significant changes to ongoing transcription in response to ethanol treatment. Further experiments revealed some ethanol-upregulated genes are sensitive to the dose of alcohol treatment, while others are not. Gene ontology and biochemical pathway analyses revealed that ethanol-upregulated genes in MCF10A cells are enriched in biological functions that could contribute to cancer development.

2023-08-04 | GSE221280 | GEO

Lactobacillus acetotolerans

Project description:Transcriptome responses of Lactobacillus acetotolerans F28 to a short and long term ethanol stress

| PRJNA358482 | ENA

Surfacome analysis of Lactobacillus rhamnosus GG and Lactobacillus rhamnosus Lc705

Project description:The present study reports comparative surfacomics (study of cell-surface exposed proteins) of the probiotic Lactobacillus rhamnosus strain GG and the dairy strain Lc705.

2016-07-01 | PXD001201 | Pride

Transcriptomic reprogramming of Ethanol adapted vs Ethanol non adapted culture

Project description:We have previously shown that fed-batch processes with the longest uncoupling phase (ethanol adapted) were characterized by induction of storage carbohydrates, a metabolic event typical of yeast cells experiencing nutrient limitation, at the onset of this phase, whereas this metabolic event was not seen in processes with a short uncoupling phase (ethanol non adapted culture). Taken together, our results suggested that reproducible high bioethanol performance in aerated fed-batch process may be linked to the ability of yeast cells to impede ethanol toxicity by triggering a metabolic remodelling reminiscent to that of cells entering a quiescent G0/G1 state. The aim of this study was to search for genes implicated in the induction an ethanol adapted culture vs ethanol non-adapted culture.

2009-09-01 | GSE15321 | GEO

Response to bile of Lactobacillus casei BL23

Project description:The response to bile of Lactobacillus casei BL23 was investigated.

2011-10-20 | GSE33047 | GEO