Genomics

Dataset Information

0

Expression data from mouse kidney


ABSTRACT: Hypertension is a major risk factor for chronic kidney disease (CKD) and renal inflammation is an integral part in this pathology. Hydrogen sulfide (H2S) has been shown to mitigate renal damage through reduction in blood pressure and reactive oxygen species; however, the exact mechanisms are not clear. While several studies have underlined the role of epigenetics in renal inflammation and dysfunction, the mechanisms through which epigenetic regulators play role in hypertension are not well defined. We used microarrays to detail the global programme of gene expression underlying hypertension in the kidney and how hydrogen sulfide supplementation alleviates these effects.

ORGANISM(S): Mus musculus synthetic construct

PROVIDER: GSE92857 | GEO | 2016/12/23

SECONDARY ACCESSION(S): PRJNA358623

REPOSITORIES: GEO

Similar Datasets

2013-07-30 | GSE16975 | GEO
| E-GEOD-16975 | biostudies-arrayexpress
2019-07-09 | GSE133942 | GEO
2021-12-24 | GSE192351 | GEO
2012-06-15 | GSE30025 | GEO
2022-05-27 | GSE131820 | GEO
2021-09-04 | GSE119429 | GEO
2021-10-12 | GSE121270 | GEO
| E-MTAB-10954 | biostudies-arrayexpress
2015-07-22 | GSE59241 | GEO